Pharmacokinetics and transcriptional effects of the anti-salmon lice drug emamectin benzoate in Atlantic salmon (Salmo salar L.)

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Pharmacokinetics and transcriptional effects of the anti-salmon lice drug emamectin benzoate in Atlantic salmon (Salmo salar L.)

BACKGROUND Emamectin benzoate (EB) is a dominating pharmaceutical drug used for the treatment and control of infections by sea lice (Lepeophtheirus salmonis) on Atlantic salmon (Salmo salar L). Fish with an initial mean weight of 132 g were experimentally medicated by a standard seven-day EB treatment, and the concentrations of drug in liver, muscle and skin were examined. To investigate how EB...

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Commercial trials using emamectin benzoate to control sea lice Lepeophtheirus salmonis infestations in Atlantic salmon Salmo salar.

Two trials were conducted at commercial salmon farms to evaluate the efficacy of emamectin benzoate (Slice, 0.2% aquaculture pre-mix, Schering-Plough Animal Health) as a treatment for sea lice Lepeophtheirus salmonis (Krøyer) and Caligus elongatus Nordmann infestations in Atlantic salmon Salmo salar L. Trials were carried out in 15 m2 commercial sea pens, at temperatures of 5.5 to 7.5 degrees C...

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Atlantic salmon – Salmo salar

Distribution Th e species’ range encompasses Europe, North America, and Green land (1) (Fig.1). Non-anadromous forms occur in Europe in a few land-locked locations in Norway and Sweden, and throughout the Neva/Lake Ladoga system and Karelia regions of Russia. In North America non-anadromous forms occurred throughout most of the species’ historical range, as far west as Lake Ontario, and remain ...

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Lysozyme transgenic Atlantic salmon (Salmo salar L.)

Disease outbreaks are a major constraint to salmon aquaculture worldwide. Therefore, there is considerable interest in ¢nding means to alleviate this problem by enhancing their innate immune system. Because lysozyme is an important component of this system, we generated a line of transgenic Atlantic salmon using a gene construct consisting of a rainbow trout lysozyme gene under the control of t...

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Control of sea lice on farmed Atlantic salmon S. salar L. with the oral treatment Emamectin benzoate (SLICE)

The use of orally administered emamectin benzoate (SLICE) to control sea lice was assessed for all stock on two salmon farms. Contrasting treatment regimes were used with two oral treatments in farm E in the second production year and one oral treatment in farm L with follow up with bath treatments. Emamectin benzoate surface coated on feed was administered as 50 ug kg1 fish biomass day-1 over ...

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ژورنال

عنوان ژورنال: BMC Pharmacology

سال: 2008

ISSN: 1471-2210

DOI: 10.1186/1471-2210-8-16